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Main - General Chat - Life extension through supplements and vitamins New thread | New reply

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Kironide
Posted on 07-09-11 09:48 PM (rev. 3 of 07-09-11 09:50 PM) Link | Quote | ID: 144778


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I have been looking into life extension lately, so that I'm more likely to be able to live until life-extension technologies become available to the common consumer. I want to develop a regimen of supplements and vitamins, and thought that it would be interesting to collaboratively develop this sort of thing so we can all live longer.

A compilation of biogerontology resources: http://www.quora.com/What-are-some-good-resources-for-aging-research-biogerontology
A story of dubious veracity, but intriguing nevertheless: http://en.wikipedia.org/wiki/Li_Ching-Yuen

There's a lot of information out there but not all of it is organized as well as it could be. Your thoughts?

I don't really want to die.

blackhole89
Posted on 07-09-11 09:53 PM Link | Quote | ID: 144780


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I am quite skeptical about vitamins beyond "keeping oneself supplied to meet the requirements of one's metabolism" possibly having any kind of life-extending effect. It's a thesis that has notoriously little to go for it apart from a few famous people from fields with little to do with medicine (I'm thinking of this gentleman) advocating it, and perhaps more notably, at least for more basic organisms (but including even mice), calorie restriction and general undersupplying of their metabolic processes has actually a significantly better body of evidence for it (cf. heaps of papers a quick Google search would produce). This might not be the case for longevity, but as far as general health goes, it seems plausible to assume (as with many other things that evolution had millions of years to optimize over) that we have landed in a local minimum and small, uninformed changes to lifestyle won't be able to yield significant improvement.

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Nick
Posted on 07-09-11 09:54 PM Link | Quote | ID: 144781


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exercise

eat right

get laid

grab life by the balls

Don't worry, Kiro. Fear of death is natural, you just need to face it head on. You're going to die some day, just live your life to your best and you have nothing to worry about.



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Haz
Posted on 07-09-11 10:01 PM Link | Quote | ID: 144782


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Posted by Kironide
I don't really want to die.

Your work will be your immortality.

Kironide
Posted on 07-09-11 10:07 PM Link | Quote | ID: 144783


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Yes, but there are many supplements that could help one avoid the onset of disease. For example, it's been shown numerous times that intake of an additional 1000 IU of vitamin D significantly reduces risk for various forms of cancer from 30% to 50%. Even though the amounts of vitamins that we obtain through a healthy and balanced diet are enough to keep us alive and well away from outright deficiencies, supplementation often has beneficial results. Even if it's not 'life extension' outright, reducing my chance of contracting some ultimately fatal illness is just as fine. To cite a more obscure example, gotu kola (Centella asiatica) has shown to have anti-tumor formation properties in several studies. I certainly think that it's at least worth considering adding some vitamins or supplements to one's daily diet for preventative purposes.

I've also been looking into calorie restriction, which seems so far to have a slew of benefits for its practitioners. I may begin to practice it after my body is, for the most part, finished growing.

Xeruss
Posted on 07-10-11 01:32 AM Link | Quote | ID: 144791


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Well then, as an American the very first thing you'll want to do is examine heart disease. Most over the counter foods here are loaded with saturated fat and excess sodium, both of which can, if not properly used by the body, contribute to heart disease.
My suggestion to you is to figure out what your blood pressure is and if it needs to go up or down. If it needs to go up, try taking yohimbe. If it needs to go down, try CoQ10.

As far as CoQ10 goes, while it may be expensive, I have noticed then when I take it for extended periods, my heart rate does not rise as much, even shortly after vigorous exercise. My heart tends to feel almost more "rested" while on CoQ10.
It's often sold in extremely high doses, but the very most I ever took was 200mg a day.

Resveratrol is also receiving a fair bit of notice lately, as, despite being a phenol, it may help prevent cancer. In large doses, it's been found to reduce blood sugar significantly, and may have some heart-protection effects.

All-in-all, taking supplements won't extend your old-age-death level, but they could potentially help prevent heart disease and cancer. Really though, the best changes most people can make are to increase daily physical activity and reduce sugar, salt, and fat consumption. Sadly, we don't have magic pills. Yet.

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Haz
Posted on 07-10-11 03:20 AM Link | Quote | ID: 144793


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Like I said in IRC. When it's my time, I'm going out in a blaze of glory, surrounded by hookers and blow, leaving mountains of debt to my children.

Xeruss
Posted on 07-10-11 03:21 AM Link | Quote | ID: 144794


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Posted by Haz
hookers and blow
I think those are the opposite of vitamins.

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PYRATROOPER
Posted on 07-10-11 07:59 PM (rev. 2 of 07-10-11 07:59 PM) Link | Quote | ID: 144821


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Posted by Haz
Like I said in IRC. When it's my time, I'm going out in a blaze of glory, surrounded by hookers and blow, leaving mountains of debt to my children.


ME TO. Anyway it sound like you are having a mid life crisis or something.

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Trelior
Posted on 07-10-11 09:28 PM Link | Quote | ID: 144823


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Posted by Xeruss
Posted by Haz
hookers and blow
I think those are the opposite of vitamins.

Posted by Dr Tran
Cocaine is like vitamins to Hotel Soap

Maybe Haz is Hotel Soap, just without the perfumed balls, because he's not cool enough to have them.

Haz
Posted on 07-10-11 11:05 PM Link | Quote | ID: 144827


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Posted by PYRATROOPER
Posted by Haz
Like I said in IRC. When it's my time, I'm going out in a blaze of glory, surrounded by hookers and blow, leaving mountains of debt to my children.


ME TO. Anyway it sound like you are having a mid life crisis or something.

It's not my time yet.


Flan
Posted on 07-12-11 01:21 AM Link | Quote | ID: 144865


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Posted by Xeruss
words

This is strongly implied, but vigorous exercise like free weights (with an emphasis on higher weights and not a billion repetitions) or high intensity interval trainingreally helps, and it's definitely the fastest way for getting out of a physical rut, and progress is very measurable.

You don't need to go overboard or anything with protein shakes or lifting a million pounds, but generally a healthy person can do stuff like deadlifts and squats at half body mass easily and work from there (I guess bench presses and stuff are good too but start with a low mass and work up). Remember you'll only put on as much muscle as your protein intake dictates, and you don't need to be "buff" or anything, it's just one of the faster, easier ways to stay healthy. It only take a few minutes every other day or so and it'll save you effort on the nutrition side too.

Just make sure you find someone reliable to show you how to start out with the weights so you have proper form (this is really important!).

Trax
Posted on 07-12-11 09:06 PM Link | Quote | ID: 144903


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Saturated fats are not responsible for cardio-vascular diseases...
Get over it...

Kironide
Posted on 07-12-11 09:21 PM Link | Quote | ID: 144905


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Posted by Trax
Saturated fats are not responsible for cardio-vascular diseases...
Get over it...


I'm fairly sure it's been proven beyond any reasonable doubt that there is indeed a connection.

Xeruss
Posted on 07-12-11 11:39 PM Link | Quote | ID: 144918


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According to the Diet-Heart Hypothesis, saturated fats raise serum levels of cholesterol, which thereby increases your risk of heart attack. Saturated fats don't directly have such an effect, if they are properly used by the body in something like vigorous physical activity.

However, if you are consuming a diet high in saturated fats without much physical activity, it will increase your risk of heart attack.

Really, the only truly 'bad' fats are partially-hydrogenated trans-fats.

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Flan
Posted on 07-13-11 06:10 AM Link | Quote | ID: 144928


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Posted by Xeruss
According to the Diet-Heart Hypothesis, saturated fats raise serum levels of cholesterol, which thereby increases your risk of heart attack. Saturated fats don't directly have such an effect, if they are properly used by the body in something like vigorous physical activity.

However, if you are consuming a diet high in saturated fats without much physical activity, it will increase your risk of heart attack.

Really, the only truly 'bad' fats are partially-hydrogenated trans-fats.

This has always seemed weird to me, but are there really fat deposits which you "can't lose" or are much more difficult to lose? I know that these days a lot of places have completely or almost completely phased out partially-hydrogenated trans-fats.

I always thought it was more related to the correlation between eating badly, exercising less and less, losing muscle and overall getting into bad shape which all seem to be related.

Xeruss
Posted on 07-13-11 06:57 AM Link | Quote | ID: 144929


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Posted by Flan
This has always seemed weird to me, but are there really fat deposits which you "can't lose" or are much more difficult to lose?

This was only touched on briefly in the chemistry course I took, but the teacher said pretty plainly that there is concern that some partially-hydrogenated fats may be unusable by the body like other fats, yet still represent natural fats enough that the body stores them, essentially adding fat to the body that can never be removed.

Although truly, the body can't actually 'lose' any fat cells after it creates them. They just release the triaglycerol they store and sort of just shrink. The only way to permanently remove a fat cell is surgery.


I always thought it was more related to the correlation between eating badly, exercising less and less, losing muscle and overall getting into bad shape which all seem to be related.
I would agree with you there, it seems any one of those can trigger the others and harm your overall health. It's a pretty slippery slope. :/

Although under current American standards for nutrition facts, if a product contains less than 1 gram per serving of trans fats, the manufacturer is allowed to list "0 grams of trans-fats per serving." However, they cannot list "absolutely no trans-fats," so if you're particularly cautious of your intake, it's a good thing to keep in mind.

I mention this because most margarines still tout themselves as a healthy alternative to butter, despite that they contain trans-fats. Considering all the label trickery at the common manufacturer's disposal, it's easy to be mislead about the healthful qualities of a product.

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Synthetekh
Posted on 08-11-11 03:25 AM (rev. 3 of 08-11-11 03:34 AM) Link | Quote | ID: 145829


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Eat plenty of vegetables and fruit and avoid the really junky foods (if you can really even call them food...) and the things that are very high in sugar, at least most of the time (it's best to get your sugars from fruits anyway). Don't skip out on your calorie intake though. This is where a lot of people go wrong. They tend to think it's either one or the other. Dairy is very congestive and hard for the body to handle (it was made for cows, not us). Too much dairy will make you sick a lot. Your body is a system of tubes, if it gets cloged up, it won't work right (and any toxins that your take in, won't be able to be cleared out very well). And pretty much anything in excess is bad, even vitamins (you can eat plenty of the good foods without worrying, it's hard to get too much of those). Physical excercise is important of course, and so is getting the right amount of sleep (whatever feels right for you is fine). The best way to extend your life, is to get healthy, and stay that way. A lot of these things are hard to keep up on, but as long as you get your sleep, exclude things from your diet that make you sick easily, and get some physical activity throughout the day (doesn't even have to be an excercise routine), you'll be alright. And the most important things is, don't be afraid of what might come in the future, that will only help to ensure failure. Just observe, be conscious and aware of what you can, and do your best as much as your feel able to.
One more thing: the best keep secret is that natural foods are the best thing for you, and why wouldn't they be, they were designed specifically for the biological body. Scientists will never find the answers they're looking for if they ignore this simple thing.

Xeruss
Posted on 08-11-11 03:44 AM Link | Quote | ID: 145830


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Posted by Synthetekh
Dairy is very congestive and hard for the body to handle (it was made for cows, not us). Too much dairy will make you sick a lot.


I would disagree with this statement. Lately, dairy is getting a bad rap, and preaching against it has become a sort of "health trend." I would put it almost on par with the way gluten-free diets are trending now, and Atkins was big five years ago, although the milk debate has been going on far longer.

The simple fact is, if the body wasn't supposed to handle milk, it wouldn't produce lactase. Many lactose-intolerant individuals are simply those who do not consume lactose on a frequent enough basis to give the body need to produce the necessary enzyme. If you don't use it, you lose it.

There's really nothing wrong with a glass of milk, it's a good source of protein, and even contains some B12; which is necessary for optimum metabolic function.

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Haz
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